InsightversusQuagmire with Compound HIV Transgenics
نویسندگان
چکیده
منابع مشابه
Insight versus Quagmire with compound HIV transgenics.
“Why don’t you mate mouse X with mouse Y and see what happens?” How many times has one heard that bit of advice? For the beleaguered postdoc assigned to this experiment, the undoubted conclusion will be: Talk is cheap. Actually completing this experiment is expensive, labor-intensive, and time-consuming. The popularity of transgenic cross-breeding studies stems from the wide availability of num...
متن کاملHumoral response suppression observed with CD23 transgenics.
CD23, also known as the low affinity IgE receptor (FcepsilonRII), has been hypothesized to have a role in IgE regulation. A new CD23 transgenic mouse was generated using the MHC class I promoter and IgH enhancer to further test the hypothesis that CD23 plays a role in the down-regulation of IgE. Study of three founder lines by FACS showed overexpression to varying extents on both B and T lympho...
متن کاملAlgal Transgenics and Biotechnology
Transgenesis in algae is a complex and fast-growing technology. Selectable marker genes, promoters, reporter genes, transformation techniques, and other genetic tools and methods are already available for various species and currently ~25 species are accessible to genetic transformation. Fortunately, large-scale sequencing projects are also planned, in progress, or completed for several of thes...
متن کاملNTP Talks Transgenics
It is indeed a pleasure and a privilege to be asked to give this lecture in memory of a fine medical scientist, whose career was cut so sadly short by violence. In looking at the program today I cannot help but think of another scientist, to whom this field owes so much, whose life was also cut short unexpectedly. Alick Isaacs, the discoverer of interferon, was a brilliant medical scientist and...
متن کاملRetinal processing: Visionary transgenics
Two recent reports in which transgene techniques were used to label specific cell classes in the mouse retina have opened the way to new methods of studying retinal signal processing.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2009
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2009080811